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Complex enzymatic electron transfer mechanisms for energy conversion

Date: Monday, January 28, 2019 09:00 - 10:00
Speaker: Ross Milton (Stanford University)
Location: Mondi Seminar Room 2, Central Building
Series: Life Sciences Seminar
Host: Johann Danzl

Metalloenzymes are central to many biologically-important reactions such as photosynthetic energy conversion and carbon dioxide reduction. Some metalloenzymes employ intricate electron transfer networks and mechanisms to perform catalysis, such as nitrogen fixation to ammonia. My research seminar will highlight key efforts to couple electron-transferring metalloenzymes with electrodes in order to study their electron transfer mechanisms and develop new biotechnological approaches to industrially-important processes. I will present recent research into an emerging electron transfer mechanism (flavin-based electron bifurcation) whereby enzymes can transfer electrons over unusually large distances in order to conserve energy. In another example I will discuss the electron transfer mechanism of the only metalloenzyme known to break the triple bond of molecular nitrogen, nitrogenase. Finally, my talk will conclude by outlining my future research interests and ambitions.
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