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Structural synaptic plasticity as a basis for spaced learning

Date: Monday, September 19, 2022 11:30 - 12:30
Speaker: Kristen M. Harris (University of Texas at Austin)
Location: Raiffeisen Lecture Hall
Series: Institute colloquium
Host: Peter Jonas
Contact: Arinya Eller
Central building lecture hall

The postsynaptic density comprises regions associated with presynaptic docked vesicles in the active zones (AZ), and nascent zones (NZ) without presynaptic vesicles. Induction of LTP recruits presynaptic vesicles to the NZs, converting them to AZs thereby stabilizing new nanocolumns between vesicles and postsynaptic receptors. Later, new NZs are built allowing augmentation of LTP as a mechanism for the advantage of spaced over massed learning.

Relevant publications:

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